About the Article

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[This article belongs to Volume - 70, Issue - 10]

Published on : 2025-10-12 21:38:57

Article Code: AMJ-12-10-2025-12353

Title : Transient Global Amnesia Following COVID-19 Vaccination: A Case Report

Author(s) : Dr. Mikhail Volkov, Dr. Irina Sokolova

Abstract :
The roles of the nervous system in the aftermath of COVID-19 vaccination is currently being studied more thoroughly.
Here, we present a case of transient global amnesia (TGA) that occurred in a 44-year-old male shortly after receiving
the Pfizer COVID-19 vaccine. The patient experienced sudden and profound anterograde amnesia with no associated
focal neurological deficits. His symptoms included seizures that lasted for less than 24-hours post-vaccination. His
test results, including chest X-ray, EEG, and a brain MRI, were negative. We aim to investigate the potential link
between the vaccination and development of TGA by providing a case description with documented clinical
presentations and diagnostic workup in order to establish any temporal association between the COVID-19
vaccination and the onset of TGA, including the vaccine type, and the time elapsed between vaccination and the
symptoms onset. This case contributes to the emerging understanding of potential neurological events following
COVID-19 vaccination. It underscores the importance of close monitoring for unusual post-vaccination symptoms
and encourages further investigations into the mechanisms underlying TGA post-vaccination. Timely diagnosis and
supportive care were crucial in the patient’s recovery.

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