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Azerbaijan Medical Journal

Aim and Scope

Azerbaijan Medical Journal

The Azerbaijan Medical Journal (AMJ) is a peer-reviewed, open-access monthly publication dedicated to advancing medical science and clinical practice through the dissemination of high-quality, original research. The Journal aims to serve as a global platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical reviews, and evidence-based insights that contribute to the understanding, prevention, diagnosis, and treatment of diseases.

AMJ welcomes submissions across a broad spectrum of medical disciplines, including but not limited to:

The Journal particularly encourages contributions from early-career researchers, multidisciplinary teams, and authors from underrepresented regions. All manuscripts undergo rigorous double-blind peer review to ensure scientific integrity, methodological soundness, and relevance to contemporary medical challenges.We invite authors worldwide to submit original articles, review papers, case reports, brief communications, and study protocols that align with the Journal’s mission of promoting excellence, equity, and accessibility in medical scholarship.

📝 Official Submission Process

Manuscripts must be submitted officially through our online system. Please complete the REGISTRATION FORM on our website first to access your Author Dashboard. You may then submit your manuscript for an initial review by our dedicated editorial team to assess its compliance with our journal's policies and scope.

Step-by-Step Submission Process:
  1. 1. Complete registration Form
  2. 2. Access Your Applicant Dashboard
  3. 3. Submit a new article
  4. 4. Fill Out the Submission Form.
    Please ensure you provide a title and abstract for your article, and upload the required document files.
    Accepted formats are PDF, TXT, and DOCX (up to 10MB per file). You may upload up to 5 files.
    The first document file is mandatory.
💡 Need Help?

For technical assistance with submission or registration, please contact:

For general editorial questions or policy inquiries:

Latest Articles

Azerbaijan Medical Journal

AMJ-14-02-2025-12311
The Gut Microbiome-Derived Metabolite TMAO as a Modulator of Immune Checkpoint Inhibitor Efficacy in Non-Small Cell Lung Cancer

Author(s): Dr. Jean-Pierre Dubois, Dr. Mei Ling Chen

Abstract: Gut microbiome composition influences immunotherapy responses, yet specific metabolite mediators remain unidentified. We show that trimethylamine N-oxide (TMAO), produced by gut microbiota from dietary choline, directly impairs CD8+ T-cell effector function through mTORC1 pathway inhibition and mitochondrial dysfunction. Elevated plasma TMAO levels (>6.5 μM) correlated with poor progression-free survival (PFS) in 240 NSCLC patients receiving pembrolizumab. Conversely, pharmacological blo...
Read More Azerbaijan Medical Journal • 14-02-2025
AMJ-14-02-2025-12310
Organ-on-Chip Modeling of Rare Ciliopathies: Joubert Syndrome Patient-Derived Kidney Tubuloids for Personalized Drug Screening

Author(s): Dr. Nora Andersen, Dr. Carlos Mendez

Abstract: Joubert syndrome (JS) renal manifestations lack disease-specific treatments and models. We generated kidney tubuloids from JS patient urine-derived induced pluripotent stem cells and integrated them into a microfluidic organ on-chip system recapitulating tubular flow and mechanical strain. These tubuloids displayed defective ciliogenesis, abnormal planar cell polarity, and perturbed calcium signaling characteristic of JS. High-content screening of 1,200 FDA-approved compounds identified r...
Read More Azerbaijan Medical Journal • 14-02-2025
AMJ-08-01-2025-12309
Focused Ultrasound-Mediated Blood-Brain Barrier Opening Enables Amyloid-β Immunotherapy in Cerebral Amyloid Angiopathy Without Microhemorrhage Risk

Author(s): Dr. William Chen, Dr. Fatima Al-Zahra, Dr. Robert Klein

Abstract: Cerebral amyloid angiopathy (CAA) complicates Alzheimer's immunotherapy due to vessel-associated amyloid and microhemorrhage risk. We employed MRI-guided focused ultrasound (FUS) with microbubbles to achieve localized, reversible blood-brain barrier (BBB) opening in Tg-SwDI mice modeling CAA. FUS-enhanced delivery of aducanumab resulted in 70% reduction of vascular amyloid without increased cerebral microbleeds observed in systemic high dose regimens. Histological analysis confirmed reduc...
Read More Azerbaijan Medical Journal • 08-01-2025
AMJ-08-01-2025-12308
Metabolic Reprogramming of Tumor-Associated Macrophages via ACLY Inhibition Reverses Immunosuppression in Ovarian Cancer

Author(s): Dr. Laura Johnson, Dr. Michael Osei

Abstract: Tumor-associated macrophages (TAMs) in the ovarian cancer ascites microenvironment exhibit protumoral M2 polarization driven by enhanced lipogenesis. Targeting ATP-citrate lyase (ACLY) with the specific inhibitor SB-204990 blocked histone acetylation at M2-associated gene loci (MRC1, CD163) while promoting inflammatory gene expression. ACLY inhibition in TAMs restored CD8+ T-cell proliferation and interferon-γ production in co-culture assays. In an orthotopic ovarian cancer model, combin...
Read More Azerbaijan Medical Journal • 08-01-2025
AMJ-11-12-2024-12307
DNA Origami Nanostructures as Precision Delivery Vehicles for CRISPR Ribonucleoproteins in Duchenne Muscular Dystrophy

Author(s): Dr. Kevin Park

Abstract: In vivo delivery of CRISPR-Cas9 for Duchenne muscular dystrophy (DMD) requires muscle-specific targeting and reduced immunogenicity. We designed tubular DNA origami nanostructures (DONs) functionalized with myostatin derived peptides for sarcolemmal targeting. These DONs encapsulated Cas9-guide RNA ribonucleoproteins (RNPs) targeting the DMD exon 51 splice site. Intramuscular injection in mdx mice achieved 35% exon skipping in myofibers, restored dystrophin expression, and improved grip s...
Read More Azerbaijan Medical Journal • 11-12-2024
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